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Hemorheological disorders in diabetes mellitus
Journal article   Open access   Peer reviewed

Hemorheological disorders in diabetes mellitus

Young I Cho, Michael P Mooney and Daniel J Cho
Journal of diabetes science and technology, v 2(6), pp 1130-1138
Nov 2008
PMID: 19885302
url
https://doi.org/10.1177/193229680800200622View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

erythrocyte deformability and aggregation hemorheological disorders microangiopathy diabetes mellitus blood viscosity
The objective of the present study is to review hemorheological disorders in diabetes mellitus. Several key hemorheological parameters, such as whole blood viscosity, erythrocyte deformability, and aggregation, are examined in the context of elevated blood glucose level in diabetes. The erythrocyte deformability is reduced, whereas its aggregation increases, both of which make whole blood more viscous compared to healthy individuals. The present paper explains how the increased blood viscosity adversely affects the microcirculation in diabetes, leading to microangiopathy.

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