Journal article
Hepatitis B Virus-Mediated Changes of Apolipoprotein mRNA Abundance in Cultured Hepatoma Cells
Journal of virology, v 77(9), pp 5503-5506
May 2003
PMID: 12692252
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
An inverse correlation between hepatitis B virus (HBV) and steady-state levels of apolipoprotein AI and CIII mRNAs was observed in two hepatoma cell lines. Analysis of a third line containing an inducible viral genome implicated viral pregenomic RNA in apolipoprotein mRNA reduction. We conclude that HBV alters infected cells despite the absence of overt cytopathogenicity.
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Details
- Title
- Hepatitis B Virus-Mediated Changes of Apolipoprotein mRNA Abundance in Cultured Hepatoma Cells
- Creators
- Pamela A Norton - Jefferson Center for Biomedical Research and Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University, Doylestown, PennsylvaniaQiaoke Gong - Jefferson Center for Biomedical Research and Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University, Doylestown, PennsylvaniaAnand S Mehta - Jefferson Center for Biomedical Research and Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University, Doylestown, PennsylvaniaXuanyong Lu - Jefferson Center for Biomedical Research and Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University, Doylestown, PennsylvaniaTimothy M Block - Jefferson Center for Biomedical Research and Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University, Doylestown, Pennsylvania
- Publication Details
- Journal of virology, v 77(9), pp 5503-5506
- Publisher
- American Society for Microbiology
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000182297200048
- Scopus ID
- 2-s2.0-0037405177
- Other Identifier
- 991014877655804721
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- Web of Science research areas
- Virology