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Journal article
Highly Flexible Precisely Braided Multielectrode Probes and Combinatorics for Future Neuroprostheses
Frontiers in neuroscience, v 13, pp 613-613
18 Jun 2019
PMID: 31275102
Abstract
The braided multielectrode probe (BMEP) is an ultrafine microwire bundle interwoven into a precise tubular braided structure, which is designed to be used as an invasive neural probe consisting of multiple microelectrodes for electrophysiological neural recording and stimulation. Significant advantages of BMEPs include highly flexible mechanical properties leading to decreased immune responses after chronic implantation in neural tissue and dense recording/stimulation sites (24 channels) within the 100–200 μm diameter. In addition, because BMEPs can be manufactured using various materials in any size and shape without length limitations, they could be expanded to applications in deep central nervous system (CNS) regions as well as peripheral nervous system (PNS) in larger animals and humans. Finally, the 3D topology of wires supports combinatoric rearrangements of wires within braids, and potential neural yield increases. With the newly developed next generation micro braiding machine, we can manufacture more precise and complex microbraid structures. In this article, we describe the new machine and methods, and tests of simulated combinatoric separation methods. We propose various promising BMEP designs and the potential modifications to these designs to create probes suitable for various applications for future neuroprostheses.
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Details
- Title
- Highly Flexible Precisely Braided Multielectrode Probes and Combinatorics for Future Neuroprostheses
- Creators
- Taegyo Kim - Drexel UniversityKendall Schmidt - Drexel UniversityChristopher Deemie - Drexel UniversityJoanna Wycech - , , , ,Hualou Liang - Drexel UniversitySimon F. Giszter - Drexel University
- Publication Details
- Frontiers in neuroscience, v 13, pp 613-613
- Publisher
- Frontiers Media S.A
- Grant note
- Pennsylvania Department of Health Division of Information and Intelligent Systems National Institute of Neurological Disorders and Stroke National Institute of Biomedical Imaging and Bioengineering
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy; School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000472041300001
- Scopus ID
- 2-s2.0-85068528660
- Other Identifier
- 991019169568304721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Neurosciences