Journal article
Highly active antiretroviral therapy-induced immune recovery in an HIV-positive patient with a history of herpes zoster ophthalmicus
Optometry (Saint Louis, Mo.), v 82(2), pp 77-82
01 Feb 2011
PMID: 21147041
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
With the introduction of highly active antiretroviral therapy (HAART), the incidence of opportunistic infections in human immunodeficiency virus (HIV)-positive patients has dramatically decreased; however, clinicians should be made aware of the clinical presentation of immune recovery–mediated HAART–induced ocular inflammation. This case report discusses the correlation of HAART induction with immune recovery and ocular inflammation in an HIV-positive patient with a history of herpes zoster ophthalmicus (HZO).
An HIV-positive man presented with a chief complaint of headache, severe facial pain, swollen eyelid, and light sensitivity in the right eye. The patient indicated the ocular discomfort was similar to his HZO outbreak treated successfully 3 months prior. He recently was initiated on HAART by his infectious disease specialist. The patient’s diagnosis was immune recovery–mediated HAART–induced ocular inflammation associated with HZO.
HAART has significantly reduced HIV-related morbidity and mortality, but new complications have emerged. Recognition of immune reconstitution inflammatory syndrome and the correlation with ocular inflammation is critical because treatment is based on protecting the patient against the effects of the inflammatory response without compromising antimicrobial or antiviral therapy.
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Details
- Title
- Highly active antiretroviral therapy-induced immune recovery in an HIV-positive patient with a history of herpes zoster ophthalmicus
- Creators
- Jean Marie Pagani - Salus UniversityJennifer Qian Duan - Manhattan Institute for Policy Research
- Publication Details
- Optometry (Saint Louis, Mo.), v 82(2), pp 77-82
- Publisher
- Elsevier
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000291708500007
- Scopus ID
- 2-s2.0-79151469683
- Other Identifier
- 991022022509704721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Ophthalmology