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Historical redlining and cardiovascular health: The Multi-Ethnic Study of Atherosclerosis
Journal article   Open access

Historical redlining and cardiovascular health: The Multi-Ethnic Study of Atherosclerosis

Mahasin S Mujahid, Xing Gao, Loni P Tabb, Colleen Morris and Tené T Lewis
Proceedings of the National Academy of Sciences - PNAS, v 118(51)
21 Dec 2021
PMID: 34903653
url
https://doi.org/10.1073/pnas.2110986118View
Published, Version of Record (VoR)CC BY V4.0 Open

Abstract

Aged Aged, 80 and over Atherosclerosis - epidemiology Atherosclerosis - ethnology Female Health Status Disparities Heart Disease Risk Factors Humans Male Middle Aged Prospective Studies Racial Groups Racism Residence Characteristics Social Environment United States - epidemiology
We investigated historical redlining, a government-sanctioned discriminatory policy, in relation to cardiovascular health (CVH) and whether associations were modified by present-day neighborhood physical and social environments. Data included 4,779 participants (mean age 62 y; SD = 10) from the baseline sample of the Multi-Ethnic Study of Atherosclerosis (MESA; 2000 to 2002). Ideal CVH was a summary measure of ideal levels of seven CVH risk factors based on established criteria (blood pressure, fasting glucose, cholesterol, body mass index, diet, physical activity, and smoking). We assigned MESA participants' neighborhoods to one of four grades (A: best, B: still desirable, C: declining, and D: hazardous) using the 1930s federal Home Owners' Loan Corporation (HOLC) maps, which guided decisions regarding mortgage financing. Two-level hierarchical linear and logistic models, with a random intercept to account for participants nested within neighborhoods (i.e., census tracts) were used to assess associations within racial/ethnic subgroups (non-Hispanic White, non-Hispanic Black, Hispanic, and non-Hispanic Chinese). We found that Black adults who lived in historically redlined areas had a 0.82 (95% CI -1.54, -0.10) lower CVH score compared to those residing in grade A (best) neighborhoods, in a given neighborhood and adjusting for confounders. We also found that as the current neighborhood social environment improved the association between HOLC score and ideal CVH weakened ( < 0.10). There were no associations between HOLC grade and CVH measures or effect modification by current neighborhood conditions for any other racial/ethnic group. Results suggest that historical redlining has an enduring impact on cardiovascular risk among Black adults in the United States.

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