Files and links (1)
Accepted (AM)Open Access (License Unspecified), Open
Journal article
Home-Based Therapy for Symptomatic Convergence Insufficiency in Children: A Randomized Clinical Trial
Optometry and vision science, v 93(12), pp 1457-1465
01 Dec 2016
PMID: 27575992
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose. To compare the effectiveness of home-based (HB) computer vergence/accommodative therapy (HB-C) to HB near target push-up therapy (HB-PU) and to HB placebo treatment (HB-P) among children aged 9 to G18 years with symptomatic convergence insufficiency (CI).
Methods. In this multicenter randomized clinical trial, participants were randomly assigned to computer therapy, near target push-ups, or placebo. All therapy was prescribed for 5 days per week at home. A successful outcome at 12 weeks was based on meeting predetermined composite criteria for the CI Symptom Survey, near point of convergence, and positive fusional vergence at near.
Results. A total of 204 participants were randomly assigned to HB-C (n = 75), HB-PU (n = 85), or HB-P (n = 44). At 12 weeks, 16 of 69 (23%, 95% CI: 14-35%) in the HB-C group, 15 of 69 (22%, 95% CI: 13Y33%) in the HB-PU group, and 5 of 31 (16%, 95% CI: 5-34%) in the HB-P group were classified as having a successful outcome. The difference in the percentage of participants with a successful outcome in the HB-C group compared with the HB-PU group was -4% (two-sided 97.5% CI: -19 to + 11%; p = 0.56) and with the HB-P group was + 5% (two-sided 97.5% CI: -12 to + 22%; p = 0.52), adjusted for baseline levels of the composite outcome components.
Conclusions. The majority of participants with symptomatic CI did not have a successful outcome at 12 weeks. Some participants treated with placebo were successful. With recruitment reaching only 34% of that originally planned and differential loss to follow-up among groups, estimates of success are not precise and comparisons across groups are difficult to interpret.
Metrics
Details
- Title
- Home-Based Therapy for Symptomatic Convergence Insufficiency in Children: A Randomized Clinical Trial
- Creators
- Mitchell M. Scheiman - Jaeb Ctr Hlth Res, 15310 Amberly Dr,Suite 350, Tampa, FL 33647 USAPediatric Eye Disease Investigator Group
- Publication Details
- Optometry and vision science, v 93(12), pp 1457-1465
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 9
- Grant note
- U10EY011751 / NATIONAL EYE INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) EY011751; EY023198; EY018810 / National Eye Institute of National Institutes of Health, Department of Health and Human Services; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000389671500002
- Scopus ID
- 2-s2.0-84984680085
- Other Identifier
- 991021900610904721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Ophthalmology