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Hormonal Responses to Dextroamphetamine in Depressed and Normal Adolescents
Journal article   Open access

Hormonal Responses to Dextroamphetamine in Depressed and Normal Adolescents

G. SCOTT Waterman, NEAL D. Ryan, JOAQUIM PUIG-ANTICH, VIVECA Meyer, PAUL J. Ambrosini, HARRIS Rabinovich, STACY Stull, HANA Novacenko, DOUGLAS E. Williamson and BEVERLY Nelson
Journal of the American Academy of Child and Adolescent Psychiatry, v 30(3), pp 415-422
May 1991
DOI: https://doi.org/10.1097/00004583-199105000-00010
PMID: 2055877
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1097/00004583-199105000-00010View
Published, Version of Record (VoR)CC BY-NC-ND V4.0,  Open

Abstract

adolescence amphetamine depression neuroendocrine
Because of its neuroendocrine effects, amphetamine infusion has been used as a probe to investigate neurobiological correlates of depressive illness. In two separate studies, a total of 72 adolescents with major depressive disorder and 66 normal adolescents were given dextroamphetamine, 0.15 mg/kg, intravenously. Their cortisol, growth hormone, and prolactin responses were measured. These endocrine responses did not reliably distinguish adolescents with major depressive disorder from those without it, nor did they reliably delineate any specific depressive subgroup. These findings are compared with those from similar studies of adult depression.

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6 citations in Web of Science
7 citations in Scopus

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UN Sustainable Development Goals (SDGs)

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#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Pediatrics
Psychiatry
Psychology, Developmental
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