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Hospitalizations among people with Down syndrome: A nationwide population-based study in Denmark
Journal article   Open access   Peer reviewed

Hospitalizations among people with Down syndrome: A nationwide population-based study in Denmark

Jin Liang Zhu, Henrik Hasle, Adolfo Correa, Diana Schendel, J. M. Friedman, Jorn Olsen and Sonja A. Rasmussen
American journal of medical genetics. Part A, v 161A(4), pp 650-657
01 Apr 2013
PMID: 23404922
url
https://europepmc.org/articles/pmc4415492View
Accepted (AM)Open Access (License Unspecified) Open

Abstract

Genetics & Heredity Life Sciences & Biomedicine Science & Technology
Most persons with Down syndrome (DS) now survive to adulthood, but their health care needs beyond childhood are not well described. We followed a national cohort of 3,212 persons with DS and a reference cohort of persons without DS through the Danish National Hospital Register from January 1, 1977, to May 31, 2008. Poisson regression was used to calculate rate ratios for numbers of overnight hospital admissions and hospital days. During the study period, persons with DS had more than twice the rate of hospital admissions and nearly three times as many bed-days as the population as a whole. Malformations, diseases of the respiratory system, and diseases of the nervous system or sensory organs were the principal indications for hospital admissions. The higher rate ratios for hospital admissions were seen especially among persons less than 20 years of age. Hospitalizations for neoplasms or for diseases of the musculoskeletal system or connective tissue were much less frequent among adults with DS. As survival among persons with DS continues to improve, these findings are likely to be useful for health care planning, although the potential utility may be different for different health care systems. (c) 2013 Wiley Periodicals, Inc.

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Genetics & Heredity
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