Genetics & Heredity Life Sciences & Biomedicine Science & Technology
Most persons with Down syndrome (DS) now survive to adulthood, but their health care needs beyond childhood are not well described. We followed a national cohort of 3,212 persons with DS and a reference cohort of persons without DS through the Danish National Hospital Register from January 1, 1977, to May 31, 2008. Poisson regression was used to calculate rate ratios for numbers of overnight hospital admissions and hospital days. During the study period, persons with DS had more than twice the rate of hospital admissions and nearly three times as many bed-days as the population as a whole. Malformations, diseases of the respiratory system, and diseases of the nervous system or sensory organs were the principal indications for hospital admissions. The higher rate ratios for hospital admissions were seen especially among persons less than 20 years of age. Hospitalizations for neoplasms or for diseases of the musculoskeletal system or connective tissue were much less frequent among adults with DS. As survival among persons with DS continues to improve, these findings are likely to be useful for health care planning, although the potential utility may be different for different health care systems. (c) 2013 Wiley Periodicals, Inc.
Sonja A. Rasmussen - Centers for Disease Control and Prevention
Publication Details
American journal of medical genetics. Part A, v 161A(4), pp 650-657
Publisher
Wiley
Number of pages
8
Grant note
U10DD000230 / CENTERS FOR DISEASE CONTROL AND PREVENTION; United States Department of Health & Human Services; Centers for Disease Control & Prevention - USA
5 U10 DD000230-06 / U.S. Centers for Disease Control and Prevention (CDC); United States Department of Health & Human Services; Centers for Disease Control & Prevention - USA
Resource Type
Journal article
Language
English
Academic Unit
A.J. Drexel Autism Institute
Web of Science ID
WOS:000316631300004
Scopus ID
2-s2.0-84875486933
Other Identifier
991021463454804721
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