Journal article
Iatrogenic solid tumors following immunosuppressive therapy
Seminars in diagnostic pathology, v 35(4), pp 272-278
Jul 2018
PMID: 29066044
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Immunosuppression induced by chronic medication, such as occurs post-transplantation, may increase a patient's risk of developing solid tumors. These are often rare tumors characterized by odd presentations. This review focuses on commonly encountered iatrogenic, non-hematopoietic solid tumors following immunotherapy and provides a practical approach to their diagnosis. All of the malignancies covered in this review are viral-induced. They include human papillomavirus (HPV)-associated carcinomas, Epstein-Barr virus (EBV)-associated tumors, Merkel cell polyomavirus (MCPyV)-related Merkel cell carcinoma, and Human Herpesvirus 8 (HHV8)-related Kaposi sarcoma. The complementary diagnostic role of ancillary studies, such as immunohistochemistry and in-situ hybridization that target these oncogenic viruses, is addressed.
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Details
- Title
- Iatrogenic solid tumors following immunosuppressive therapy
- Creators
- Kossivi Dantey - Allegheny General HospitalLiron Pantanowitz - University of Pittsburgh Medical Center
- Publication Details
- Seminars in diagnostic pathology, v 35(4), pp 272-278
- Publisher
- Elsevier
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pathology (and Laboratory Medicine)
- Web of Science ID
- WOS:000435890100008
- Scopus ID
- 2-s2.0-85031741700
- Other Identifier
- 991021930444004721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Medical Laboratory Technology
- Pathology