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Impact of BMI on clinically significant unsuspected findings as determined at postmortem examination
Journal article   Open access   Peer reviewed

Impact of BMI on clinically significant unsuspected findings as determined at postmortem examination

S Gabriel, E J Gracely and B S Fyfe
American journal of clinical pathology, v 125(1)
01 Jan 2006
PMID: 16483001
url
https://doi.org/10.1309/nvvmpb3dtfrgw3vvView
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

Life Sciences & Biomedicine Science & Technology Pathology
We conducted a retrospective cohort study based on autopsy reports of 311 patients who underwent full postmortem examinations from January 1, 1999, to December 31, 2002. Clinically unsuspected diagnoses were categorized as follows: class I, major clinically unsuspected diagnoses that were responsible for death; class H, major clinically unsuspected diagnoses that were not directly responsible for death but if left undiagnosed may have resulted in patient death; and class V, no clinically unsuspected diagnoses. Two multivariate analyses were performed using 4 variables to predict class I diagnoses. Both analyses inclucled the variables sex, race, and age; the fourth variable included umbilicus pannus size or body mass index (BMI). Only BMI (P = .006) and umbilicus pannus size (P = .037) were independent predictors of class I diagnoses. Obese patients were 1.65 times more likely (relative risk, 1.65) to have a class I diagnosis than the normal weight and underweight groups combined (confidence interval. 1.04-2.64). Patients with obese-level BMIs seem to be at increased risk for clinically significant unsuspected diagnoses compared with underweight and normal weigh populations.

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Web of Science research areas
Pathology
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