Journal article
Impact of COVID-19 on Initial Management and Evaluation of Prostate Cancer
Urology practice, v 8(6), pp 668-674
01 Nov 2021
PMID: 37145514
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Introduction: The COVID-19 pandemic starkly affected all aspects of health care, forcing many to divert resources towards emergent patient needs while decreasing emphasis on routine cancer care. We compared prostate cancer care before and during the pandemic in a multi-institutional cohort.
Methods: A prospective regional collaborative was queried to assess practice pattern variations relative to the initial COVID-19 lockdown (March 16 to May 15, 2020). The preceding 10 months were selected for comparison. The impact of the lockdown was evaluated on the basis of 1) weekly trends in biopsy and radical prostatectomy volumes, 2) comparisons between those undergoing prostate biopsy, and 3) clinicopathological characteristics within radical prostatectomy patients. Categorical variables were compared using Fisher's exact and Pearson's chi-square tests, and Wilcoxon rank sum test to evaluate continuous covariates.
Results: Overall, there was a 55% and 39% decline in biopsy and prostatectomy volumes, respectively. During the pandemic, biopsy patients were younger with fewer COVID-19 severity risk factors (17.0% vs 9.7% no risk factors, p=0.023) and prostatectomy patients had higher grade group (GG; 45.6% >GG 4 vs 28%, p=0.01). Large variation in the change in procedural volume was noted across practice sites.
Conclusion: In a multi-institutional assessment of surgical and diagnostic delay for prostate cancer, we found a non-uniform decline in procedural volume across sites. Future analyses within this cohort are needed to further discern the effects of care delays related to COVID-19.
Metrics
Details
- Title
- Impact of COVID-19 on Initial Management and Evaluation of Prostate Cancer
- Creators
- Adrien N. Bernstein - Fox Chase Cancer CenterRuchika Talwar - University of PennsylvaniaElizabeth Handorf - Fox Chase Cancer CenterKaynaat Syed - Hlth Care Improvement Fdn, Philadelphia, PA USAJohn Danella - Geisinger Health SystemSerge Ginzburg - Einstein Healthcare NetworkLaurence Belkoff - Main Line HealthAdam C. Reese - Temple UniversityJeffery Tomaszewski - Cooper University Health CareEdouard Trabulsi - Thomas Jefferson UniversityBruce Jacobs - University of PittsburghEric A. Singer - Rutgers, The State University of New JerseyJay Raman - Penn State Milton S. Hershey Medical CenterMarc Smaldone - Fox Chase Canc Ctr, 7701 Burholme Ave, Philadelphia, PA 19111 USARobert Uzzo - Fox Chase Cancer CenterThomas Guzzo - University of PennsylvaniaAndres Correa - Fox Chase Cancer Center
- Publication Details
- Urology practice, v 8(6), pp 668-674
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 7
- Grant note
- National Cancer Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Surgery
- Web of Science ID
- WOS:000756925300017
- Scopus ID
- 2-s2.0-85128925238
- Other Identifier
- 991021916910704721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Urology & Nephrology