Journal article
Impact of Stroke Risk Factors on Ethnic Stroke Disparities Among Midlife Mexican Americans and Non-Hispanic Whites
Stroke (1970), v 48(10), pp 2872-2874
01 Oct 2017
PMID: 28935697
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background and Purpose-We examined the contribution of stroke risk factors to midlife (age 45-59 years) Mexican American and non-Hispanic White ischemic stroke (IS) rate disparities from 2000 to 2010.
Methods-Incident IS cases (n = 707) and risk factors were identified from the Brain Attack Surveillance in Corpus Christi Project, Nueces County, TX (2000-2010). US Census data (2000-2010) were used to estimate the population at-risk for IS, and the Behavioral Risk Factor Surveillance System (2000-2010) was used to estimate risk factor prevalence in the stroke-free population. Poisson regression models combined IS counts (numerator) and population at-risk counts (denominator) classified by ethnicity and risk factor status to estimate unadjusted and risk factor-adjusted associations between ethnicity and IS rates. Separate models were run for each risk factor and extended to include an interaction term between ethnicity and risk factor.
Results-The crude rate ratio (RR) for ethnicity (Mexican American versus non-Hispanic White) was 2.01 (95% confidence interval [CI], 1.71-2.36) and was attenuated in models that adjusted for diabetes mellitus (RR: 1.50; 95% CI, 1.26-1.78) and hypertension (RR: 1.84; 95% CI, 1.50-2.26). In addition, diabetes mellitus had a stronger association with IS rates among Mexican Americans (RR: 6.42; 95% CI, 5.31-7.76) compared with non-Hispanic Whites (RR: 4.07; 95% CI, 3.68-4.51).
Conclusions-The higher prevalence of diabetes mellitus and hypertension and stronger association of diabetes mellitus with IS among midlife Mexican Americans likely contribute to persistent midlife ethnic stroke disparities.
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Details
- Title
- Impact of Stroke Risk Factors on Ethnic Stroke Disparities Among Midlife Mexican Americans and Non-Hispanic Whites
- Creators
- Rajiv C. Patel - Virginia Commonwealth UniversityBrisa N. Sanchez - University of MichiganLewis B. Morgenstern - NeurologyChengwei Li - Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USALynda D. Lisabeth - Samuel and Jean Frankel Cardiovascular Center
- Publication Details
- Stroke (1970), v 48(10), pp 2872-2874
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 10
- Grant note
- R01NS038916 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) R01NS38916; R01NS070941 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA American Heart Association P30DK092926 / NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000411572500056
- Scopus ID
- 2-s2.0-85030750351
- Other Identifier
- 991020100200404721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Peripheral Vascular Disease