Journal article
Impact of an Antimicrobial Stewardship Team on Reducing Antiretroviral Medication Errors
The Annals of pharmacotherapy, v 54(8), pp 767-774
01 Aug 2020
PMID: 31973571
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background: Numerous interventions have been used to reduce medication errors related to antiretroviral (ARV) therapy for hospitalized patients with HIV. Objective: This study assessed the impact of an antimicrobial stewardship (ASP) team intervention on reducing the rate of ARV therapy errors in patients admitted to an academic medical center. Methods: This observational, retrospective study included patients who received ARV therapy from June 2016 to December 2017. The primary outcome was evaluation of ASP team performance in detecting ARV medication errors in the inpatient setting. Errors were further categorized by type (interaction, dosing, regimen). The Mann-Whitney U test and chi(2) tests were utilized to analyze continuous and categorical data, respectively. Results: Medication errors occurred in 51% of patients in the preintervention group (n = 152) and 48% of patients in the postintervention group (n = 203; P = 0.43). The most frequent medication error type was drug interactions in both groups, involving integrase strand transfer inhibitors and polyvalent cations (64% vs 67%). There was a significant difference between preintervention and postintervention groups regarding number of errors detected (13 vs 106, P < 0.001), corrected (12 vs 86, P < 0.001), and persisting at discharge (106 vs 18, P < 0.001). Conclusion and Relevance: Review of ARV regimens by an ASP team significantly decreased medication errors. Drug interactions are the most common medication error found in HIV-positive patients admitted to our academic center.
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Details
- Title
- Impact of an Antimicrobial Stewardship Team on Reducing Antiretroviral Medication Errors
- Creators
- Kwabena Nimarko - Hahnemann University HospitalAiman Bandali - Hahnemann University HospitalTiffany E. Bias - Hahnemann University HospitalSharon Mindel - Hahnemann University Hospital
- Publication Details
- The Annals of pharmacotherapy, v 54(8), pp 767-774
- Publisher
- Sage
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000509205600001
- Scopus ID
- 2-s2.0-85078331329
- Other Identifier
- 991019330626104721
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- Web of Science research areas
- Pharmacology & Pharmacy