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Improving Recruitment and Retention of Transgender Women in HIV Prevention Trials: Strategies to Make Trial Participation More Congruent with the Needs of Transgender Women
Journal article   Open access   Peer reviewed

Improving Recruitment and Retention of Transgender Women in HIV Prevention Trials: Strategies to Make Trial Participation More Congruent with the Needs of Transgender Women

Doyel Das, Javier Lopez-Rios, Stacey A McKenna, Jonathan Porter, Curtis Dolezal, Pilar Giffenig, Michael Patrick Vaughn, Elena Abascal, Jasmine Michelle Lopez and Christine Tagliaferri Rael
AIDS research and human retroviruses, v 40(12), pp 680-689
Dec 2024
PMID: 39003524
url
https://pmc.ncbi.nlm.nih.gov/articles/PMC11693950/pdf/aid.2023.0063.pdfView
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Abstract

Adult Anti-HIV Agents - administration & dosage Anti-HIV Agents - therapeutic use Clinical Trials as Topic Diketopiperazines Female HIV Infections - prevention & control Humans Interviews as Topic Male Middle Aged New York City Patient Selection Pre-Exposure Prophylaxis - methods Pyridones Transgender Persons - psychology Transgender Persons - statistics & numerical data Young Adult
Transgender women are disproportionately burdened by HIV. Though there is a substantial body of research exploring barriers and facilitators of HIV prevention among transgender women, many barriers remain unaddressed. This study identifies strategies to make HIV prevention trials more congruent with transgender women's preferences and needs to boost trial participation and ultimately enhance initiation and uptake of pre-exposure prophylaxis (PrEP). We conducted in-depth interviews with 15 sexually active, HIV-negative transgender women in New York City to understand: (1) preferences concerning long-acting injectable cabotegravir for PrEP and (2) ideas on how to make HIV prevention trial environments more comfortable. We identified five themes related to increasing transgender women's appeal to trials: (1) creating a more inclusive/welcoming environment, (2) providing compensation that is responsive to transgender women and community needs, (3) centering transgender women in recruitment and informational materials, (4) training study staff on gender-affirming practices, and (5) hiring transgender people as study staff. Participants wanted to see more gender diversity, representation, correct pronouns, gender-affirming practices, and compensation or reimbursements. Together, these practices may improve recruitment and retention of transgender women in HIV prevention trials.

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#5 Gender Equality
#3 Good Health and Well-Being

InCites Highlights

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Collaboration types
Domestic collaboration
Web of Science research areas
Immunology
Infectious Diseases
Virology
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