Journal article
Improving Risk Assessment of Miscarriage During Pregnancy with Knowledge Graph Embeddings
Journal of healthcare informatics research, v 5(4), pp 359-381
01 Dec 2021
PMID: 35419509
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Miscarriages are the most common type of pregnancy loss, mostly occurring in the first 12 weeks of pregnancy. Pregnancy risk assessment aims to quantify evidence to reduce such maternal morbidities, and personalized decision support systems are the cornerstone of high-quality, patient-centered care to improve diagnosis, treatment selection, and risk assessment. However, data sparsity and the increasing number of patient-level observations require more effective forms of representing clinical knowledge to encode known information that enables performing inference and reasoning. Whereas knowledge embedding representation has been widely explored in the open domain data, there are few efforts for its application in the clinical domain. In this study, we contrast differences among multiple embedding strategies, and we demonstrate how these methods can assist in performing risk assessment of miscarriage before and during pregnancy. Our experiments show that simple knowledge embedding approaches that utilize domain-specific metadata perform better than complex embedding strategies, although both can improve results comparatively to a population probabilistic baseline in both AUPRC, F1-score, and a proposed normalized version of these evaluation metrics that better reflects accuracy for unbalanced datasets. Finally, embedding approaches provide evidence about each individual, supporting explainability for its model predictions in such a way that humans understand.
Metrics
Details
- Title
- Improving Risk Assessment of Miscarriage During Pregnancy with Knowledge Graph Embeddings
- Creators
- Hegler C. Tissot - Universidade Federal do ParanáLucas A. Pedebos - Universidade Federal de Santa Catarina
- Publication Details
- Journal of healthcare informatics research, v 5(4), pp 359-381
- Publisher
- Springer Nature
- Number of pages
- 23
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Information Science
- Web of Science ID
- WOS:000654164600001
- Scopus ID
- 2-s2.0-85105396216
- Other Identifier
- 991021861654404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Computer Science, Information Systems
- Health Care Sciences & Services
- Medical Informatics