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Imputation of Missing Data in Electronic Health Records Based on Patients’ Similarities
Journal article   Open access

Imputation of Missing Data in Electronic Health Records Based on Patients’ Similarities

Ali Jazayeri, Ou Stella Liang and Christopher C. Yang
Journal of healthcare informatics research, v 4(3), pp 295-307
2020
DOI: https://doi.org/10.1007/s41666-020-00073-5
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1007/s41666-020-00073-5View
Published, Version of Record (VoR)Open Access (License Unspecified),  Open

Abstract

Biomedical Engineering and Bioengineering Computational Biology/Bioinformatics Computational Intelligence Computer Science Data Mining and Knowledge Discovery Health Informatics Research Article
Using electronic health records (EHR) as the source of data for mining and analysis of different health conditions has become an increasingly common approach. However, due to irregular observation times and other uncertainties inherent in medical settings, the EHR data sets suffer from a large number of missing values. Most of the traditional data mining and machine learning approaches are designed to operate on complete data. In this paper, we propose a novel imputation method for missing data to facilitate using these approaches for the analysis of EHR data. The imputation is based on a set of interpatient, multivariate similarities among patients. For a missing data point in a patient’s lab results during his/her intensive care unit stay, the method ranks other patients based on their similarities with the ego patient in terms of lab values, then the missing value is estimated as a weighted average of the known values of the same laboratory test from other patients, considering their similarities as weights. A comparison of the estimated values by the proposed method with values estimated by several common and state-of-the-are methods, such as MICE and 3D-MICE, shows that the proposed method outperforms them and produces promising results.

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29 citations in Web of Science
30 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

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Web of Science research areas
Computer Science, Information Systems
Health Care Sciences & Services
Medical Informatics
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