Journal article
In-Hospital Outcomes of Coronary Artery Stenting in Patients With ST-Elevation Myocardial Infarction (STEMI) and Metabolic Syndrome: Insights From the National Inpatient Sample
Curēus (Palo Alto, CA), v 14(5), pp e24664-e24664
02 May 2022
PMID: 35663720
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background
Metabolic syndrome (MetS) has been recognized as a global health problem. Concurrent MetS diagnosis in patients with ST-elevation myocardial infarction (STEMI) is becoming increasingly common. Given the paucity of studies on the impact of MetS on treatment outcomes in STEMI patients, the purpose of this study was to evaluate in-hospital mortality in STEMI patients with a concurrent MetS diagnosis undergoing a stenting procedure to treat their underlying coronary artery disease.
Method
Patients with or without MetS who underwent coronary stenting following STEMI between 2005 and 2014 were identified from the National Inpatient Sample database. Patients' demographics, comorbidities, and outcomes were compared using a t-test and Pearson's Chi-square test. In addition, 1:1 propensity score matching was performed for age, gender, and race.
Results
Out of 1,938,097 STEMI patients, 5,817 patients with MetS underwent coronary stenting following STEMI and were matched with 5,817 patients with no Mets. MetS group had significantly higher rates of diabetes, hypertension, hyperlipidemia, chronic kidney disease, and obstructive sleep apnea than the no MetS group but lower rates of heart failure and chronic obstructive pulmonary disease. In-hospital mortality following STEMI was significantly lower in patients with MetS (2.5% vs. 7.1%, p<0.001) and remained significant after adjusting for potential confounders (odds ratio (OR) 0.34, 95% confidence interval (95% CI) 0.28-0.42, p<0.0001).
Conclusion
Concurrent diagnosis of MetS among patients undergoing coronary stenting is associated with a decreased in-hospital mortality risk. The impact of specific MetS components on the observed reduction in mortality remains unclear and warrants evaluation in future studies.
Metrics
8 Record Views
Details
- Title
- In-Hospital Outcomes of Coronary Artery Stenting in Patients With ST-Elevation Myocardial Infarction (STEMI) and Metabolic Syndrome: Insights From the National Inpatient Sample
- Creators
- Owen Igbinosa - Howard University HospitalAhmed Brgdar - Howard University HospitalJoseph Asemota - Howard University HospitalMohamed E Taha - Howard University HospitalJin Yi - Howard University HospitalAnthony Lyonga Ngonge - Howard University HospitalSwati Vanaparthy - Howard University HospitalRaccquel Hammonds - Howard University HospitalJoseph Talbet - Howard University HospitalDiannemarie Omire-Mayor - Howard University HospitalJulius Ngwa - Howard University HospitalMuhammad Rizwan - Howard University HospitalMehrotra Prafulla - Howard University HospitalIsaac Opoku - Howard University HospitalDaryl O Omire-Mayor - School of Biomedical Engineering, Science, and Health Systems (1997-)
- Publication Details
- Curēus (Palo Alto, CA), v 14(5), pp e24664-e24664
- Publisher
- Cureus
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems; Drexel University
- Web of Science ID
- WOS:000800317900001
- Other Identifier
- 991019415661904721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cardiac & Cardiovascular Systems