Journal article
In Utero Exposure to Selective Serotonin Reuptake Inhibitors and Risk for Autism Spectrum Disorder
Journal of autism and developmental disorders, v 44(10), pp 2558-2567
Oct 2014
PMID: 24803368
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We investigated whether there is an association between increased risk for autism spectrum disorders (ASD) and selective serotonin reuptake inhibitors (SSRIs) used during pregnancy. This study used Denmark’s health and population registers to obtain information regarding prescription drugs, ASD diagnosis, and health and socioeconomic status. There were 1.5 % of cases and 0.7 % of controls exposed to SSRIs during the pregnancy period, and higher effect estimates observed with longer use. We found evidence that in utero exposure to SSRIs increases a child’s risk associated with ASD. These results, while adding to the limited knowledge on prenatal pharmacological exposures as potential ASD risk factors, need to be balanced against the benefits of indicated medication use by pregnant mothers.
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Details
- Title
- In Utero Exposure to Selective Serotonin Reuptake Inhibitors and Risk for Autism Spectrum Disorder
- Creators
- Nicole Gidaya - Drexel University, School of Public Health, Nesbitt Hall 3215 Market Street Philadelphia PA 19104 USABrian Lee - Drexel University, School of Public Health, Nesbitt Hall 3215 Market Street Philadelphia PA 19104 USAIgor Burstyn - Drexel University, School of Public Health, Nesbitt Hall 3215 Market Street Philadelphia PA 19104 USAMichael Yudell - Drexel University, School of Public Health, Nesbitt Hall 3215 Market Street Philadelphia PA 19104 USAErik Mortensen - Institut for Folkesundhedsvidenskab University of Copenhagen Øster Farimagsgade 5, bygn. 15, stuen 1353 Copenhagen K DenmarkCraig Newschaffer - A.J. Drexel Autism Institute Drexel University 3020 Market Street, Suite 560 Philadelphia PA 19104 USA
- Publication Details
- Journal of autism and developmental disorders, v 44(10), pp 2558-2567
- Publisher
- Springer US; Boston
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics; A.J. Drexel Autism Institute; Community Health and Prevention; Environmental and Occupational Health
- Web of Science ID
- WOS:000342211800017
- Scopus ID
- 2-s2.0-84912027605
- Other Identifier
- 991014878021404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Psychology, Developmental