Journal article
In vitro activity of RP 59500 (quinupristin/dalfopristin) against antibiotic-resistant strains of Streptococcus pneumoniae and Enterococci
Diagnostic microbiology and infectious disease, v 21(3), pp 169-173
1995
PMID: 7648837
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The activity of RP 59500 (quinupristin/dalfopristin) was evaluated in vitro against antibiotic-resistant strains of
Streptococcus pneumoniae (N = 15) and
Enterococcus spp. (N = 43). By broth dilution MIC tests RP 59500 was highly active against penicillin-resistant
S. pneumoniae and vancomycin-resistant
Enterococcus faecium, but showed poor activity against
E. faecalis. In time-kill studies the drug was rapidly bactericidal against
S. pneumoniae but failed to kill most enterococci, even in the presence of gentamicin or human serum.
Metrics
Details
- Title
- In vitro activity of RP 59500 (quinupristin/dalfopristin) against antibiotic-resistant strains of Streptococcus pneumoniae and Enterococci
- Creators
- Caroline C. Johnson - Drexel UniversityLinda Slavoski - Drexel UniversityMary Schwartz - Drexel UniversityPhyllis May - Drexel UniversityPeter G. Pitsakis - Drexel UniversityAndrew L. Shur - Drexel UniversityMatthew E. Levison - Drexel University
- Publication Details
- Diagnostic microbiology and infectious disease, v 21(3), pp 169-173
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Medicine (Graduate); Dana and David Dornsife School of Public Health
- Web of Science ID
- WOS:A1995RD46800006
- Scopus ID
- 2-s2.0-0029001363
- Other Identifier
- 991019184054104721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Infectious Diseases
- Microbiology