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In-vitro and in-vivo comparison of mezlocillin and cefoxitin
Journal article   Peer reviewed

In-vitro and in-vivo comparison of mezlocillin and cefoxitin

J. L. LeFrock, A. Molavi, K. Rolston, B. Smith, R. Schell, P. Chandrasekar and B. Carr
Journal of antimicrobial chemotherapy, v 11(suppl-C), pp 83-90
1983
DOI: https://doi.org/10.1093/jac/11.suppl_C.83
PMID: 6352609
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

The efficacy, toxicity, microbiology and pharmacology of cefoxitin and mezlocillin were compared in a clinical and laboratory study. In 81 patients treated with cefoxitin and 83 treated with mezlocillin, clinical and bacteriological cures were achieved in 79.2% and 85.5% respectively. Both antibiotics were effective in the treatment of septicaemia, pulmonary infections, urinary tract infections, intra-abdominal and pelvic infections and skin and soft-tissue infections. Both were also effective in the treatment of anaerobic infections. No major haematological, hepatic, or renal toxicity was encountered in patients treated with either drug.

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5 citations in Web of Science
4 citations in Scopus

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#3 Good Health and Well-Being

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Web of Science research areas
Infectious Diseases
Microbiology
Pharmacology & Pharmacy
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