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In vitro susceptibilities of oral pigmented Bacteroides species to trospectomycin and other selected antimicrobial agents
Journal article   Open access   Peer reviewed

In vitro susceptibilities of oral pigmented Bacteroides species to trospectomycin and other selected antimicrobial agents

C C Johnson, M Wendeler and M E Levison
Antimicrobial agents and chemotherapy, v 34(8), pp 1597-1599
Aug 1990
PMID: 2145801
url
https://doi.org/10.1128/AAC.34.8.1597View
Published, Version of Record (VoR)Open Access (License Unspecified) Open

Abstract

Anti-Bacterial Agents - pharmacology Bacteroides - drug effects Drug Resistance, Microbial Microbial Sensitivity Tests Spectinomycin - analogs & derivatives Spectinomycin - pharmacology
The in vitro activity of trospectomycin against 97 clinical isolates of oral pigmented Bacteroides species was compared with the activities of five other antimicrobial agents. At 4 micrograms/ml, more than 90% of isolates were inhibited by trospectomycin. Overall, strains that produced beta-lactamase (n = 41) were more resistant to trospectomycin, penicillin G, cefoxitin, piperacillin, and tetracycline but not to clindamycin. In this study, trospectomycin had excellent in vitro activity against oral pigmented Bacteroides species.

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Collaboration types
Domestic collaboration
Web of Science research areas
Microbiology
Pharmacology & Pharmacy
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