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In vitro susceptibility of mink lung cells to the mouse mammary tumor virus
Journal article

In vitro susceptibility of mink lung cells to the mouse mammary tumor virus

E Y Lasfargues, A B Vaidya, J C Lasfargues and D H Moore
JNCI : Journal of the National Cancer Institute, v 57(2), pp 447-449
Aug 1976
PMID: 187775

Abstract

Lung - microbiology Antigens, Neoplasm Cells, Cultured Mammary Tumor Virus, Mouse - growth & development Cell Membrane - ultrastructure Pregnancy Animals Antigens, Viral Virus Replication Cell Transformation, Neoplastic Female Cell Membrane - immunology Mice Mink
Lung cells from mink embryos were infected in vitro with a purified mammary tumor virus isolated from RIII mouse milk. Specific virus antigen at the cell surface was detected by membrane immunofluorescence; B-type virions budding from the cell membrane were seen by electron microscopy. Nucleic acid hybridization confirmed replication and specificity of the virus produced.

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