Journal article
Inclusion Complexes in Drug Delivery and Drug Targeting: Formation, Characterization, and Biological Applications
Targeted nanosystems for therapeutic applications : new concepts, dynamic properties, efficiency, and toxicity
2019
Abstract
Host–guest complexation based on non-covalent interactions can be successfully exploited for drug and nucleic acid delivery purposes. The chapter covers the main classes of hosts used for these applications, namely cyclodextrins, calixarenes, and cucurbiturils and reveals the main representatives and their physicochemical characteristics that modulate the complexation process. It also highlights relevant drugs and nucleic acid complexes, together with the dysfunctions and diseases where the host–guest complexes have been successfully used.
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Details
- Title
- Inclusion Complexes in Drug Delivery and Drug Targeting: Formation, Characterization, and Biological Applications
- Creators
- Rajesh K. K. Sanku - Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N. Broad Street, Philadelphia, Pennsylvania 19140, United StatesOzlem O. Karakus - Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N. Broad Street, Philadelphia, Pennsylvania 19140, United States, Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, 1 Discovery Drive, Rensselaer, New York 12144, United StatesMonica Ilies - Drexel University, ChemistryMarc A. Ilies - Temple University
- Publication Details
- Targeted nanosystems for therapeutic applications : new concepts, dynamic properties, efficiency, and toxicity
- Publisher
- American Chemical Society; Washington, DC
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemistry
- Other Identifier
- 0841233748; 9780841233744; 991021903707004721