Neglected children's acute hypothalamic-pituitary-adrenal axis (HPA axis) reactivity in response to a laboratory visit was contrasted with that of a comparison group. The authors examined initial salivary cortisol response upon entering the laboratory and its trajectory following a set of tasks designed to elicit negative self-evaluation in 64 children (30 with a history of neglect and 34 demographically matched comparison children). Neglected, but not comparison, children showed higher initial cortisol responses. The cortisol response of both groups showed a decline from the sample taken at lab entry, with neglected children's cortisol exhibiting steeper decline. The groups, however, did not differ in their mean cortisol levels at 20 and 35 min post-task. The results are interpreted in terms of the meaning of initial responses as a "baseline" and as evidence for neglected children's heightened HPA-axis reactivity as either a reflection of differences in home levels or the consequence of stress/anxiety associated with arrival at the laboratory.
Individual Differences in the Cortisol Responses of Neglected and Comparison Children
Creators
Margaret Wolan Sullivan - Department of Pediatrics, Institute for the Study of Child Development, Robert Wood Johnson Medical School - UMDNJ, New Brunswick, NJ 08901, USA.
David S. Bennett - Drexel University
Michael Lewis - Rutgers, The State University of New Jersey
Publication Details
Child maltreatment, v 18(1), pp 8-16
Publisher
Sage
Number of pages
9
Grant note
R01 DA011153; DA1153/MH56751 / NIDA NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA)
R01MH064473 / NATIONAL INSTITUTE OF MENTAL HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
R01DA011153 / NATIONAL INSTITUTE ON DRUG ABUSE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Drug Abuse (NIDA); European Commission
R01 MH059391; R01 MH064473; MH064473 / NIMH NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
Resource Type
Journal article
Language
English
Academic Unit
Psychiatry
Web of Science ID
WOS:000318043800002
Scopus ID
2-s2.0-84875066525
Other Identifier
991019167917104721
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