Journal article
Infantile Melanoma-A Triple Threat Diagnosis and Management
Annals of plastic surgery, v 67(1), pp 85-89
01 Jul 2011
PMID: 21346539
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Cases of infantile melanoma are very rare, and only a few have been presented in the literature. Pediatric melanoma can present to the clinician as a "triple threat" of delayed diagnosis resulting in thick lesions at risk for metastasis, histologic uncertainty of diagnosis, and a lack of data guiding regional node management and adjuvant therapy. Melanoma in childhood is an uncommon condition, and it is even more atypical in infants. There is evidence however that it is increasing in frequency. We present 2 cases of infantile melanoma diagnosed before age 1 and multidisciplinary management performed at our institution. One child was diagnosed with melanoma arising within a congenital melanocytic nevus, and the other presented with melanoma from a de novo acquired scalp lesion. The ambiguity surrounding correct pathologic diagnosis of melanoma in this age group, and the tendency for late diagnosis with thicker lesions presents special staging and treatment challenges to the team of specialists involved in the care of these children.
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Details
- Title
- Infantile Melanoma-A Triple Threat Diagnosis and Management
- Creators
- Milena Lambie - Philadelphia College of Osteopathic MedicineChad Nadler - Drexel Univ, Coll Med, Dept Surg, Philadelphia, PA 19104 USAPaul Glat - Drexel UniversityScott Van Duzer - St Christophers Hosp Children, Dept Pediat Plast Surg, Philadelphia, PA 19133 USAGregory Halligan - St Christophers Hosp Children, Dept Pediat Oncol, Philadelphia, PA 19133 USAEvan Geller - St Christophers Hosp Children, Dept Radiol, Philadelphia, PA 19133 USA
- Publication Details
- Annals of plastic surgery, v 67(1), pp 85-89
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000291587200018
- Scopus ID
- 2-s2.0-79959707077
- Other Identifier
- 991019167915204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Surgery