Journal article
Influence of PCPA, shock level, and home-cage conditions on shock-induced aggression
Physiology & behavior, v 23(5), pp 897-907
Nov 1979
PMID: 160569
Abstract
In a series of experiments, the effect of parachlorophenylalanine (PCPA) on shock-induced fighting was assessed in rats raised and maintained under either a 12-hr alternating light-dark cycle (LD) or constant light conditions (LL). PCPA increased shock-induced aggression only in LL groups when testing was accomplished using a 2 mA shock; PCPA resulted in increased aggression in groups from the LD condition only when testing was done at 1 mA. A procedure that used castrated and intact cagemates to manipulate home-cage social experience provided evidence for a role for social experience in determining differences between LL and LD reared rats in shock-induced aggression. However, these data also suggested that home-cage social experience was not a factor in the lighting condition influence on the effect of PCPA on shock-induced aggression. Finally, a separate experiment demonstrated that diurnal rhythms in shock-induced aggression were disrupted by handling and vehicle injection in the control procedures, so the possible role of serotonin in diurnal rhythms of aggression behavior could not be assessed.
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Details
- Title
- Influence of PCPA, shock level, and home-cage conditions on shock-induced aggression
- Creators
- John F. Knutson - University of IowaNeal L. Kane - University of IowaArthur J. Schlosberg - University of IowaDavid J. Fordyce - University of IowaKenny J. Simansky - University of Iowa
- Publication Details
- Physiology & behavior, v 23(5), pp 897-907
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- SOM Dean - Research Administration
- Web of Science ID
- WOS:A1979HV62100017
- Scopus ID
- 2-s2.0-0018687660
- Other Identifier
- 991021842529804721