Journal article
Influence of Stressors on Breast Cancer Incidence in the Women's Health Initiative
Health psychology, v 28(2), pp 137-146
Mar 2009
PMID: 19290705
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective:
To examine associations among life events stress, social support, and breast cancer incidence in a cohort of postmenopausal women.
Design and main outcome measure:
Women's Health Initiative observational study participants, breast cancer free at entry, who provided assessment of stressful life events, social support, and breast cancer risk factors, were prospectively followed for breast cancer incidence (
n
= 84,334).
Results:
During an average of 7.6 years of follow-up, 2,481 invasive breast cancers were diagnosed. In age-adjusted proportional hazards models, 1 stressful life event was associated with increased risk, but risk decreased with each additional stressful life event. After adjustment for confounders the decreasing risk was not significant. Stressful life events and social support appeared to interact in relation to breast cancer risk such that women who had greater number of stressful life events and low social support had a decreased risk of breast cancer.
Conclusions:
This study found no independent association between stressful life events and breast cancer risk. The results are compatible with a more complex model of psychosocial factors interacting in relation to breast cancer risk.
Metrics
Details
- Title
- Influence of Stressors on Breast Cancer Incidence in the Women's Health Initiative
- Creators
- Yvonne L Michael - Department of Public Health and Preventive Medicine, Oregon Health and Science UniversityNichole E Carlson - Department of Public Health and Preventive Medicine, Oregon Health and Science UniversityRowan T Chlebowski - David Geffen School of Medicine, UCLA, and Division of Medical Oncology and Hematology, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical CenterMikel Aickin - Family and Community Medicine, University of Arizona Medical CenterKaren L Weihs - Department of Psychiatry, University of Arizona Medical CenterJudith K Ockene - Division of Preventive and Behavioral Medicine, Department of Medicine, University of Massachusetts Medical SchoolDeborah J BowenCheryl Ritenbaugh - Family and Community Medicine, University of Arizona Medical Center
- Publication Details
- Health psychology, v 28(2), pp 137-146
- Publisher
- American Psychological Association
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000264326300001
- Scopus ID
- 2-s2.0-64549108490
- Other Identifier
- 991014877891904721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychology
- Psychology, Clinical