Journal article
Influence of age-related changes on crack growth trajectories and toughening mechanisms in human dentin
Dental materials, v 38(11), 1789
29 Sep 2022
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
OBJECTIVES : Dentin microstructure undergoes changes with age and its materials properties degrade over time. In the present study, we investigate the coupled influence of increased filled tubules and decreased materials properties on the fracture behavior of human dentin.
METHODS : We assume degraded materials properties are linked with increased advanced glycation end-products (AGEs) crosslinks in dentin tissue. We use morphological data of human molars to create 2D and 3D models of dentin microstructure, and utilize a phase field fracture framework to study crack growth trajectories. We construct aged dentin samples (i.e., filled tubules and degraded properties) and compare the fracture results with the samples without age-related changes.
RESULTS : The simulations show an increase in the number of filled tubules can deactivate the toughening mechanisms such as crack deflection and microcracking. In addition, filled tubules have adverse impacts on the ability of peritubular dentin to shield microcracking. We further show how the dentinal tubules' orientations affect the crack surface growth. We also investigate that an increase in the AGEs level can result in increased brittleness.
SIGNIFICANCE : The developed model and findings of the present study provide region-dependent information on crack growth trajectories as well as more understanding of crack surface growth at the presence of filled tubules.
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Details
- Title
- Influence of age-related changes on crack growth trajectories and toughening mechanisms in human dentin
- Creators
- Ebrahim Maghami - Drexel UniversityAhmad R Najafi
- Publication Details
- Dental materials, v 38(11), 1789
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Mechanical Engineering and Mechanics
- Web of Science ID
- WOS:000877617200003
- Scopus ID
- 2-s2.0-85139057531
- Other Identifier
- 991019173884804721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Dentistry, Oral Surgery & Medicine
- Materials Science, Biomaterials