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Influence of enolate geometry and structure on the stereochemistry of the asymmetric oxidation of prochiral ketone enolates to optically active α-hydroxy ketones
Journal article   Peer reviewed

Influence of enolate geometry and structure on the stereochemistry of the asymmetric oxidation of prochiral ketone enolates to optically active α-hydroxy ketones

Franklin A. Davis, Aurelia C. Sheppard and G.Sankar Lal
Tetrahedron letters, v 30(7), pp 779-782
1989

Abstract

The stereoselectivity for the asymmetric oxidation of enolates to optically active α-hydroxy ketones using (+)-(camphorylsulfonyl)oxaziridine is dependent on the enolate substitution pattern, the solution structure of the enolate and to a lesser extent the enolate geometry. The stereoselectivity for the asymmetrix oxidation of enolates to optically active α-hydroxy ketones using (+)-(camphoryl-sulfonyl)oxaziridine is dependent on the enolate substitution pattern, the solution structure of the enolate and to a lesser extent the enolate geometry.

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Web of Science research areas
Chemistry, Organic
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