Journal article
Injectable Self-Assembling Peptide Hydrogels for Tissue Writing and Embryonic Stem Cell Culture
Journal of biomedical nanotechnology, Vol.14(4), pp.802-807
01 Apr 2018
PMID: 31352954
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The fabrication of extracellular matrix-mimic hydrogels that can nurture and direct differentiation of embryonic stem cells is an important target for pattern-printed tissue replacement. Another desirable feature for such materials is their ability to be injected and recover their rheological features post-injection, allowing for facile non-invasive implantation. In this report, we demonstrate the ability of a self-assembling peptide hydrogel to support the culture of embryonic stem cells with the potential to direct differentiation. We also show that we can write a functional tissue replacement with a predetermined pattern using our formulation. Our results may lead to in vivo replacement of diseased tissue with a spatially resolved pattern of a regenerative hydrogel.
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Details
- Title
- Injectable Self-Assembling Peptide Hydrogels for Tissue Writing and Embryonic Stem Cell Culture
- Creators
- Pamela Hitscherich - New Jersey Institute of TechnologyPeter K. Nguyen - New Jersey Institute of TechnologyAdithya Kannan - New Jersey Institute of TechnologyAnthony Chirayath - New Jersey Institute of TechnologySugosh Anur - New Jersey Institute of TechnologyBiplab Sarkar - New Jersey Institute of TechnologyEun Jung Lee - New Jersey Institute of TechnologyVivek A. Kumar - New Jersey Institute of Technology
- Publication Details
- Journal of biomedical nanotechnology, Vol.14(4), pp.802-807
- Publisher
- Amer Scientific Publishers
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- School of Biomedical Engineering, Science, and Health Systems
- Identifiers
- 991021956863004721
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- Web of Science research areas
- Materials Science, Biomaterials
- Nanoscience & Nanotechnology