Integrating automation and autonomy into self-driving laboratories promises more efficient and reproducible experimentation while freeing scientists to focus on intellectual challenges. In the rapid advances being made towards self-driving laboratories, automation and autonomy techniques are often convoluted due to similarities between them and ambiguous language, leaving the trade-offs between them overlooked. In this perspective, we address differences between making a process occur without human intervention (automation) and providing agency and flexibility in action (autonomy). We describe the challenges of autonomy in terms of (1) orchestration, how tasks are organized and coordinated; (2) facilitation, how devices are connected and brought under automated control; and (3) scripting languages, how workflows are encoded into digital representations. Autonomous systems require advanced control architectures to handle a reactive, evolving workflow, involving control abstractions and scheduling beyond what current automation approaches provide. The specification of an autonomous system requires goal-oriented commands and context awareness, whereas automation needs exact, unambiguous instructions for reproducibility and efficiency. We contend that this contrast in design creates a need for improved standards in automation and a set of guiding principles to facilitate the development of autonomy-enabling technologies.
The strict specification required for automatization to efficiently and reproducibly act in familiar domains restricts the flexibility needed for autonomy when exploring new domains, requiring self-driving labs to balance autonomy and automation.
Integrating autonomy into automated research platforms
Creators
Richard B. Canty - Massachusetts Institute of Technology
Brent A. Koscher - Massachusetts Institute of Technology
Matthew A. Mcdonald - Massachusetts Institute of Technology
Klavs F. Jensen - Massachusetts Institute of Technology
Publication Details
Digital discovery, v 2(5), pp 1259-1268
Publisher
Royal Soc Chemistry
Number of pages
10
Grant note
HR00111920025 / This work was supported by the DARPA Accelerated Molecular Discovery (AMD) program under contract HR00111920025. The authors would like to thank Dylan Walsh for intellectual discussions regarding this work.
DARPA Accelerated Molecular Discovery (AMD) program; United States Department of Defense
Resource Type
Journal article
Language
English
Academic Unit
Chemical and Biological Engineering
Web of Science ID
WOS:001101655700001
Scopus ID
2-s2.0-85173707070
Other Identifier
991021958105904721
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