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Interfacial optimization of fiber-reinforced hydrogel composites for soft fibrous tissue applications
Journal article   Peer reviewed

Interfacial optimization of fiber-reinforced hydrogel composites for soft fibrous tissue applications

Julianne L Holloway, Anthony M Lowman, Mark R VanLandingham and Giuseppe R Palmese
Acta biomaterialia, v 10(8), pp 3581-3589
Aug 2014
PMID: 24814880

Abstract

Poly(vinyl alcohol) Meniscus Hydrogel Composite Interfacial strength
Interfacial properties and the effect of inter-fiber spacing for UHMWPE-PVA hydrogel composites were analyzed, where PVA-grafted UHMWPE fibers showed significantly improved fiber-matrix stress transfer. [Display omitted] Meniscal tears are the most common orthopedic injuries to the human body, yet the current treatment of choice is a partial meniscectomy, which is known to lead to joint degeneration and osteoarthritis. As a result, there is a significant clinical need to develop materials capable of restoring function to the meniscus following an injury. Fiber-reinforced hydrogel composites are particularly suited for replicating the mechanical function of native fibrous tissues due to their ability to mimic the native anisotropic property distribution present. A critical issue with these materials, however, is the potential for the fiber–matrix interfacial properties to severely limit composite performance. In this work, the interfacial properties of an ultra-high-molecular-weight polyethylene (UHMWPE) fiber-reinforced poly(vinyl alcohol) (PVA) hydrogel are studied. A novel chemical grafting technique, confirmed using X-ray photoelectron spectroscopy, is used to improve UHMWPE–PVA interfacial adhesion. Interfacial shear strength is quantified using fiber pull-out tests. Results indicate significantly improved fiber–hydrogel interfacial adhesion after chemical grafting, where chemically grafted samples have an interfacial shear strength of 256.4±64.3kPa compared to 11.5±2.9kPa for untreated samples. Additionally, scanning electron microscopy of fiber surfaces after fiber pull-out reveal cohesive failure within the hydrogel matrix for treated fiber samples, indicating that the UHMWPE–PVA interface has been successfully optimized. Lastly, inter-fiber spacing is observed to have a significant effect on interfacial adhesion. Fibers spaced further apart have significantly higher interfacial shear strengths, which is critical to consider when optimizing composite design. The results in this study are applicable in developing similar chemical grafting techniques and optimizing fiber–matrix interfacial properties for other hydrogel-based composite systems.

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Collaboration types
Domestic collaboration
Web of Science research areas
Engineering, Biomedical
Materials Science, Biomaterials
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