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Internal architecture design and freeform fabrication of tissue replacement structures
Journal article   Peer reviewed

Internal architecture design and freeform fabrication of tissue replacement structures

B. Starly, W. Lau, T. Bradbury and W. Sun
Computer aided design, v 38(2), pp 115-124
2006
DOI: https://doi.org/10.1016/j.cad.2005.08.001
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Computer-aided tissue engineering Interior architecture Scaffold design TheriForm
Modeling, design and fabrication of tissue scaffolds with intricate architecture, porosity and pore size for desired tissue properties presents a challenge in tissue engineering. This paper will present the details of our development in the design and fabrication of the interior architecture of scaffolds using a novel design approach. The interior architecture design (IAD) approach seeks to generate layered scaffold freeform fabrication tool path without forming complicated 3D CAD scaffold models. This involves: applying the principle of layered manufacturing to determine the scaffold individual layered process planes and layered contours; defining the 2D characteristic patterns of the scaffold building blocks (unit cells) to form the Interior Scaffold Pattern; and the generating the process tool path for freeform fabrication of these scaffolds with the specified interior architecture. Feasibility studies applying the IAD algorithm to example models with multi-interior architecture and the generation of fabrication planning instructions will also be presented.

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8 Record Views
51 citations in Web of Science
61 citations in Scopus

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UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

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Web of Science research areas
Computer Science, Software Engineering
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