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Journal article
Intra- and Interrater Reliability and Concurrent Validity of a New Tool for Assessment of Breast Cancer–Related Lymphedema of the Upper Extremity
Archives of physical medicine and rehabilitation, v 100(2), pp 315-326
Feb 2019
PMID: 30291828
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The goal of this study was to develop and assess intra- and interrater reliability and validity of a clinical evaluation tool for breast cancer–related lymphedema, for use in the context of outcome evaluation in clinical trials.
Blinded repeated measures observational study.
Outpatient research laboratory.
Breast cancer survivors with and without lymphedema (N=71).
Not applicable.
The assessment of intraclass correlation coefficients (ICCs) for the Breast Cancer–Related Lymphedema of the Upper Extremity (CLUE) standardized clinical evaluation tool.
Intrarater reliability for the CLUE tool was ICC: 0.88 (95% confidence interval [95% CI], 0.71-0.96). Interrater reliability for the CLUE tool was ICC: 0.90 (95% CI, 0.79-0.95). Concurrent validity of the CLUE score (Pearson r) was 0.79 with perometric interlimb difference and 0.53 with the Norman lymphedema overall score.
The CLUE tool shows excellent inter- and intrarater reliability. The overall CLUE score for the upper extremity also shows moderately strong concurrent validity with objective and subjective measures. This newly developed clinical, physical assessment of upper extremity lymphedema provides standardization and a single score that accounts for multiple constructs. Next steps include evaluation of sensitivity to change, which would establish usefulness to evaluate intervention efficacy.
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Details
- Title
- Intra- and Interrater Reliability and Concurrent Validity of a New Tool for Assessment of Breast Cancer–Related Lymphedema of the Upper Extremity
- Creators
- Bryan Spinelli - Thomas Jefferson UniversityMichael J. Kallan - University of PennsylvaniaXiaochen Zhang - The Ohio State UniversityAndrea Cheville - Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN§Andrea Troxel - New York UniversityJoy Cohn - Good Shepherd Penn PartnersLorraine Dean - Johns Hopkins UniversityKathleen Sturgeon - Penn State Cancer InstituteMargaret Evangelista - University of PennsylvaniaZi Zhang - Harlem Hospital CenterDavid Ebaugh - Drexel UniversityKathryn H. Schmitz - Penn State Cancer Institute
- Publication Details
- Archives of physical medicine and rehabilitation, v 100(2), pp 315-326
- Publisher
- Elsevier
- Grant note
- R25MH083620 / National Institute of Mental Health (https://doi.org/10.13039/100000025) P30AI094189 / Johns Hopkins University Center for AIDS Research K01CA184288 / National Cancer Institute (https://doi.org/10.13039/100000054) P30CA006973 / Sidney Kimmel Cancer Center U54-CA155850 / National Cancer Institute (https://doi.org/10.13039/501100002387)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Physical Therapy (and Rehabilitation Sciences)
- Web of Science ID
- WOS:000458597000015
- Scopus ID
- 2-s2.0-85057820711
- Other Identifier
- 991019276215204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Rehabilitation
- Sport Sciences