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Journal article
Intracranial electroencephalography reveals effector-independent evidence accumulation dynamics in multiple human brain regions
Nature human behaviour, v 8(4), pp 758-770
Apr 2024
PMID: 38366105
Abstract
Neural representations of perceptual decision formation that are abstracted from specific motor requirements have previously been identified in humans using non-invasive electrophysiology; however, it is currently unclear where these originate in the brain. Here we capitalized on the high spatiotemporal precision of intracranial EEG to localize such abstract decision signals. Participants undergoing invasive electrophysiological monitoring for epilepsy were asked to judge the direction of random-dot stimuli and respond either with a speeded button press (N = 24), or vocally, after a randomized delay (N = 12). We found a widely distributed motor-independent network of regions where high-frequency activity exhibited key characteristics consistent with evidence accumulation, including a gradual buildup that was modulated by the strength of the sensory evidence, and an amplitude that predicted participants' choice accuracy and response time. Our findings offer a new view on the brain networks governing human decision-making.
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Details
- Title
- Intracranial electroencephalography reveals effector-independent evidence accumulation dynamics in multiple human brain regions
- Creators
- Sabina Gherman - Feinstein Institute for Medical ResearchNoah Markowitz - Feinstein Institute for Medical ResearchGelana Tostaeva - Feinstein Institute for Medical ResearchElizabeth Espinal - Drexel UniversityAshesh D Mehta - Feinstein Institute for Medical ResearchRedmond G O'Connell - Trinity College DublinSimon P Kelly - University College DublinStephan Bickel - Feinstein Institute for Medical Research
- Publication Details
- Nature human behaviour, v 8(4), pp 758-770
- Grant note
- R01 MH122513 / NIMH NIH HHS R01MH122513 / U.S. Department of Health & Human Services | National Institutes of Health (NIH)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Drexel University
- Web of Science ID
- WOS:001163667000003
- Scopus ID
- 2-s2.0-85185103811
- Other Identifier
- 991021861280204721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Neurosciences
- Psychology, Biological
- Psychology, Experimental