Journal article
Intramyocardial mechanical states: vessel-interstitium-muscle interface
Advances in experimental medicine and biology, v 346
1993
PMID: 8184750
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The intramural blood vessels and fluid-filled interstitial space form a hydraulic continuum enmeshed by myocardial muscle layers and collagen matrix. Coronary circulation was found to be strongly influenced by passive and active properties of the muscle surrounding the coronary microvasculature. Selective remodeling of the extracellular collagen-matrix and partial uncoupling of the intramyocardial structure(s) cause profound functional alterations in the coronary circulation and interstitial compartment fluid-dynamics. Mechanical impediment to coronary inflow resides in the muscle fiber-interstitium-microvessel interface, functioning independently of the generated chamber pressure conditions.
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Details
- Title
- Intramyocardial mechanical states: vessel-interstitium-muscle interface
- Creators
- J Y Kresh - Likoff Cardiovascular Institute, Department of Cardiothoracic Surgery, Philadelphia, PA 19102
- Publication Details
- Advances in experimental medicine and biology, v 346
- Publisher
- Springer Nature; United States
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1993BZ51S00011
- Scopus ID
- 2-s2.0-0027724365
- Other Identifier
- 991014878099304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Cardiac & Cardiovascular Systems
- Physiology