Journal article
Is there any advantage to three-dimensional planning for vaginal cuff brachytherapy?
Brachytherapy, v 11(5), pp 398-401
01 Sep 2012
PMID: 22301073
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
PURPOSE: To evaluate whether the three-dimensional (3D) CT-based high-dose rate planning for vaginal cuff brachytherapy offers any advantage over the 2D orthogonal film-based library plans for adjuvant treatment of endometrial cancers.
METHODS AND MATERIALS: Eighty-four consecutive postoperative patients with endometrial cancers treated with vaginal brachytherapy as an adjuvant treatment were analyzed. Patients had CT imaging-based plans. Clinical target volume (CTV) was defined by expanding the upper 2.5 cm of the cylinder by 5 mm in all directions and editing to exclude any bladder and rectum. The dose prescribed was 7 Gy with three fractions at 5 mm depth with a goal of D-90 >= 100% for CTV. All dosimetric parameters were compared with library-based plans.
RESULTS: Both the 2D- and 3D-based plans allowed sufficient dosage to the CTV (D-90 for CTV >= 95%). The doses of 0.1, 1, and 2 cc to rectum and bladder were significantly higher for 2D-based plans (p <= 0.001 in each parameter). D-2 cc with 2D plan for rectum and bladder was >100% (range: 103-116%) in 7 (8%) and 6(7%) patients, respectively. In contrast, no patients had D-2 cc >100% with 3D planning for both organs.
CONCLUSION: Three-dimensional CT-based planning for high-dose rate vaginal cuff brachytherapy helps to decrease dose to critical organs without compromising coverage of CTV by customizing the dosimetry according to individual patient anatomy. (C) 2012 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.
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Details
- Title
- Is there any advantage to three-dimensional planning for vaginal cuff brachytherapy?
- Creators
- Hyun Kim - University of PittsburghHayeon Kim - Magee-Womens HospitalChristopher Houser - University of Pittsburgh Medical CenterSushil Beriwal - Magee-Womens Hospital
- Publication Details
- Brachytherapy, v 11(5), pp 398-401
- Publisher
- Elsevier
- Number of pages
- 4
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000308626400012
- Scopus ID
- 2-s2.0-84865394454
- Other Identifier
- 991021897372604721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging