Journal article
Isonitrile alkylations: a rapid route to imidazo[1,5-a]pyridines
Chemical communications (Cambridge, England), v 52(10), pp 2111-2113
01 Jan 2016
PMID: 26691391
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Metalated arylmethylisonitriles readily add to 2-chloropyridines to afford imidazo[1,5-a]pyridines. Analogous additions to imidoyl chlorides and a chloroquinoline provide imidazoles and an imidazo[1,5-a]quinolone which, like imidazo[1,5-a]pyridines, are valuable heterocycles for pharmaceutical synthesis.
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Details
- Title
- Isonitrile alkylations: a rapid route to imidazo[1,5-a]pyridines
- Creators
- Yajun Li - Drexel UniversityAllen Chao - Duquesne UniversityFraser F. Fleming - Drexel University
- Publication Details
- Chemical communications (Cambridge, England), v 52(10), pp 2111-2113
- Publisher
- Royal Soc Chemistry
- Number of pages
- 3
- Grant note
- R15AI051352 / NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Allergy & Infectious Diseases (NIAID) 2R15AI051352-04 / NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Chemistry
- Web of Science ID
- WOS:000369585800027
- Scopus ID
- 2-s2.0-84956509697
- Other Identifier
- 991019168140204721
UN Sustainable Development Goals (SDGs)
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Source: SDGs in the Output
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Chemistry, Multidisciplinary