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Journal article
K2-Not the Spice of Life; Synthetic Cannabinoids and ST Elevation Myocardial Infarction: A Case Report
Journal of medical toxicology, v 11(1)
01 Mar 2015
PMID: 25154434
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Introduction The adverse effects of synthetic cannabinoids are not well-described nor have they been thoroughly studied.
Case Report A 16-year-old male with a past medical history of asthma and attention deficit hyperactivity disorder (ADHD) presented to the emergency department (ED) complaining of 24 h of substernal pressure associated with dyspnea, nausea, and vomiting. He reported smoking tobacco cigarettes daily and occasional marijuana use but denied recent use of marijuana. The initial electrocardiogram (EKG) revealed ST-segment elevations in leads II, III, AVF, and V4-V6. The initial troponin level was reported as 1.47 ng/mL, and the initial creatine kinase MB (CKMB) level was 17.5 ng/mL. The patient admitted to smoking "K2" 60-90 min prior to the onset of symptoms. The patient manifested persistent ST elevations with a peak troponin of 8.29 ng/mL. The urine drug immunoassay was positive for benzodiazepines and opiates. Cardiac catheterization revealed normal coronary arteries, no wall motion abnormalities, and normal systolic function.
Discussion Synthetic cannabinoids may have significant potential adverse effects. Chest pain due to myocardial ischemia is rare in adolescents. When evaluating patients with chest pain, it is important to elicit a detailed drug history, specifically inquiring about synthetic cannabinoid use. Urine drug immunoassays may be unreliable and in this case did not detect synthetic cannabinoids.
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Details
- Title
- K2-Not the Spice of Life; Synthetic Cannabinoids and ST Elevation Myocardial Infarction: A Case Report
- Creators
- Rita G. McKeever - Drexel UniversityDavid Vearrier - Drexel UniversityDorian Jacobs - Drexel UniversityGregory LaSala - Drexel UniversityJolene Oka Neku - Drexel Univ, Dept Emergency Med, Coll Med, Philadelphia, PA 19104 USAMichael Greenberg - Drexel University
- Publication Details
- Journal of medical toxicology, v 11(1)
- Publisher
- Springer Nature
- Number of pages
- 3
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine; Emergency Medicine
- Web of Science ID
- WOS:000443027400016
- Scopus ID
- 2-s2.0-84925817878
- Other Identifier
- 991019169595304721
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- Web of Science research areas
- Toxicology