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Kenalog Injection into Hunner's Lesions as a Treatment for Interstitial Cystitis/Bladder Pain Syndrome
Journal article   Open access   Peer reviewed

Kenalog Injection into Hunner's Lesions as a Treatment for Interstitial Cystitis/Bladder Pain Syndrome

Lauren Rittenberg, Darlene Morrissey, Dominique El-Khawand and Kristene Whitmore
Current urology, v 10(3), pp 154-156
Aug 2017
DOI: https://doi.org/10.1159/000447171
PMID: 28878600
url
https://doi.org/10.1159/000447171View
Published, Version of Record (VoR)CC BY-NC-ND V4.0,  Open

Abstract

Hunner's lesions Interstitial cystitis Painful bladder syndrome Kenalog
This study aims to evaluate the effectiveness of kenalog injection into Hunner's lesions. All patients had cystoscopy and bladder hydrodistention with corticosteroid injection into Hunner's lesions over a 2.5-year period. Data include patient characteristics and pre- and post-operative validated questionnaires. Spearman Correlation and Wilcoxon -tests were used for analysis. One hundred patients were reviewed retrospectively. There was a 1.1 point decrease in pain at 12 weeks post-operation (p = 0.435). Urinary frequency decreased from a mean of 11.7 to 9.1 daily episodes (p = 0.05), and nocturia from a mean of 3 to 1.6 nightly episodes (p = 0.008). The use of a corticosteroid may be beneficial to symptom control and improvement in the quality of life of interstitial cystitis/painful bladder syndrome patients. Patients had improved frequency and nocturia 12 weeks post injection.

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