Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity

Sarah E Basehore; Samantha Bohlman; Callie Weber; Swathi Swaminathan; Yuji Zhang; Cholsoon Jang; Zoltan Arany; Alisa Morss Clyne

doi:10.1161/CIRCRESAHA.121.318982

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Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity

Journal article

Open access

Peer reviewed

Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity

Sarah E Basehore, Samantha Bohlman, Callie Weber, Swathi Swaminathan, Yuji Zhang, Cholsoon Jang, Zoltan Arany and Alisa Morss Clyne

Circulation research, v 129(11), pp 1054-1066

12 Nov 2021

DOI: https://doi.org/10.1161/CIRCRESAHA.121.318982

PMID: 34605247

Featured in Collection : UN Sustainable Development Goals @ Drexel

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Abstract

Acetylglucosamine - metabolism

Animals

Blood Circulation

Blood Vessels - metabolism

Blood Vessels - physiology

Endothelium, Vascular - metabolism

Endothelium, Vascular - physiology

Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) - metabolism

Glycosylation

Human Umbilical Vein Endothelial Cells - metabolism

Humans

Mice

Mice, Inbred C57BL

N-Acetylglucosaminyltransferases - antagonists & inhibitors

N-Acetylglucosaminyltransferases - metabolism

Nitric Oxide - metabolism

Nitric Oxide Synthase Type III - metabolism

Phosphorylation

[Figure: see text].

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23 citations in Web of Science

25 citations in Scopus

Details

Title: Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity
Creators: Sarah E Basehore - University of Maryland, College Park
Samantha Bohlman - University of Maryland, College Park
Callie Weber - University of Maryland, College Park
Swathi Swaminathan - Drexel University
Yuji Zhang - Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore (Y.Z.).
Cholsoon Jang - University of California, Irvine
Zoltan Arany - University of Pennsylvania
Alisa Morss Clyne - University of Maryland, College Park
Publication Details: Circulation research, v 129(11), pp 1054-1066
Grant note: P30 DK019525 / NIDDK NIH HHS R01 HL140239 / NHLBI NIH HHS R01 HL094499 / NHLBI NIH HHS
Resource Type: Journal article
Language: English
Academic Unit: Biology
Web of Science ID: WOS:000716564600009
Scopus ID: 2-s2.0-85121957580
Other Identifier: 991019167529404721

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Collaboration types: Domestic collaboration
Web of Science research areas: Cardiac & Cardiovascular Systems; Hematology; Peripheral Vascular Disease

Laminar Flow on Endothelial Cells Suppresses eNOS O-GlcNAcylation to Promote eNOS Activity

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Abstract

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Details

UN Sustainable Development Goals (SDGs)

InCites Highlights

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