Life Sciences & Biomedicine Pediatrics Science & Technology
OBJECTIVE: The purpose of the study was to examine use of the Modified Checklist for Autism in Toddlers (M-CHAT) as an autism-specific screening instrument in a large, geographically diverse pediatrics-based sample.
METHODS: The M-CHAT and the M-CHAT Follow-Up (M-CHAT/F) were used to screen 18 989 toddlers at pediatric well-child visits in 2 US geographic regions. Pediatricians directly referred children to ascertain potential missed screening cases. Screen-positive children received the M-CHAT/F; children who continued to screen positive after the M-CHAT/F received a diagnostic evaluation.
RESULTS: Results indicated that 54% of children who screened positive on the M-CHAT and M-CHAT/F presented with an autism spectrum disorder (ASD), and 98% presented with clinically significant developmental concerns warranting intervention. An M-CHAT total score cutoff of >= 3 identifies nearly all screen-positive cases, and for ease of scoring the use of only the M-CHAT total score cutoff is recommended. An M-CHAT total score of 7 serves as an appropriate clinical cutoff, and providers can bypass the M-CHAT/F and refer immediately to evaluation and intervention if a child obtains a score of >= 7.
CONCLUSIONS: This study provides empirical support for the utility of population screening for ASD with the use of the M-CHAT in a primary care setting. Results suggest that the M-CHAT continues to be an effective screening instrument for ASD when the 2-step screening process is used. The M-CHAT is widely used at pediatric offices, and this study provides updated results to facilitate use and scoring of the M-CHAT by clinical providers.
Large-Scale Use of the Modified Checklist for Autism in Low-Risk Toddlers
Creators
Colby Chlebowski - Department of Psychiatry, University of California-San Diego, San Diego, California, USA.
Diana L. Robins - Georgia State University
Marianne L. Barton - cDepartments of Psychology and
Deborah Fein - University of Connecticut
Publication Details
Pediatrics (Evanston), v 131(4), pp E1121-E1127
Publisher
Amer Acad Pediatrics
Number of pages
7
Grant note
R40 MC00270 / Maternal and Child Health Bureau
Centers for Disease Control and Prevention-Georgia State University seed grant in the social and behavioral sciences
F31 MH12550-1-2 / National Institute of Mental Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
R01 HD039961 / National Institutes of Health (NIH); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
US Department of Education student
F31MH012550 / NATIONAL INSTITUTE OF MENTAL HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH)
National Association for Autism Research
R01HD039961 / EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Resource Type
Journal article
Language
English
Academic Unit
A.J. Drexel Autism Institute
Web of Science ID
WOS:000318269500010
Scopus ID
2-s2.0-84875983179
Other Identifier
991019186795804721
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