Journal article
Laryngopharyngeal reflux: current concepts and questions
Current opinion in otolaryngology & head and neck surgery, v 17(3)
01 Jun 2009
PMID: 19395970
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose of review
Laryngopharyngeal reflux is a widely recognized disorder. Yet, decades after its initial description, debate persists regarding pathophysiology, diagnosis, and treatment. This review addresses current literature on laryngopharyngeal reflux and identifies areas of controversy and future opportunities for research.
Recent findings
Despite numerous research efforts, the diagnosis and treatment of laryngopharyngeal reflux remain elusive and unproven. Acid-induced changes in laryngopharyngeal mucosa have been confirmed by histologic evidence. However, the implications of this for laryngeal symptoms and signs are unclear. Diagnosis remains controversial, confounded by lack of standardization and accepted, evidence-based norms. Whereas treatment is generally believed by clinicians to be effective in alleviating symptoms and signs attributed to laryngopharyngeal reflux, incontrovertible data confirming efficacy are scarce. Confounding the issues further, there are numerous studies that purport to show that various widely used treatments are not effective, although the scientific merit of virtually all of these studies has been challenged.
Summary
Laryngopharyngeal reflux remains a controversial diagnosis. Treatment with proton pump inhibitors persists despite weak evidence supporting or refuting their utility, and well designed studies are needed to understand diagnosis, treatment, pathyophysiology, and long-term health consequences of laryngopharyngeal reflux and its treatment.
Metrics
Details
- Title
- Laryngopharyngeal reflux: current concepts and questions
- Creators
- Reena Gupta - Drexel UniversityRobert Thayer Sataloff - Drexel University
- Publication Details
- Current opinion in otolaryngology & head and neck surgery, v 17(3)
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000266574900001
- Scopus ID
- 2-s2.0-67749114401
- Other Identifier
- 991019312469904721
UN Sustainable Development Goals (SDGs)
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Otorhinolaryngology