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Lethal effects of erythritol on the mosquito Aedes aegypti Linnaeus (Diptera: Culicidae)
Journal article   Open access

Lethal effects of erythritol on the mosquito Aedes aegypti Linnaeus (Diptera: Culicidae)

Patrick L Gilkey, Dennis T Bolshakov, Julia G Kowala, Linden A Taylor, Sean O'Donnell, Daniel R Marenda and Laura K Sirot
Journal of applied entomology (1986), v 142(9), pp 873-881
Nov 2018
url
https://doi.org/10.1111/jen.12538View
Published, Version of Record (VoR) Open

Abstract

yellow fever mosquito adulticide sugar alcohol larvicide vector control
The yellow fever mosquito Aedes aegypti Linnaeus is a major vector of several viruses that cause disease in humans and other animals. Conventional insecticides have been used for vector control, but can be problematic because Ae. aegypti and other mosquitoes can evolve resistance to them and they can negatively impact non‐target insect species. Therefore, there is a strong demand for novel methods in Ae. aegpyti vector control strategies. Our study investigated whether the sugar alcohol, erythritol, has potential as a novel insecticide for mosquito control. Erythritol is lethal to several dipteran species yet has been deemed safe for consumption by humans and other mammals. We tested the impact of erythritol on Ae. aegypti by comparing the longevity of larvae reared in erythritol‐treated water and adult females maintained on erythritol. We also tested whether sucrose supplementation impacts the effects of erythritol on adult longevity. For larvae, erythritol exposure at concentrations as low as 0.1 m is lethal, with LC50 at 48 hr of 0.11 m for early stage (3‐day old) larvae and 0.42 m for late stage (5‐day old) larvae. For adult females, maintenance on erythritol is lethal at concentrations as low as 0.5 m, with LC50 at 72 hr of 1.60 m. Further, a mixture of 1 m sucrose/1 m erythritol solution is more lethal to adult females than 1 m erythritol solution alone, suggesting that erythritol in combination with sucrose could comprise a toxic sugar bait. These results provide promising evidence for erythritol as a novel larvicide and adulticide for Ae. aegypti.

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Collaboration types
Domestic collaboration
Web of Science research areas
Entomology
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