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Leveraging neuroscience imaging and electrophysiological assessments to decode neuron-glioma interactions
Journal article   Open access   Peer reviewed

Leveraging neuroscience imaging and electrophysiological assessments to decode neuron-glioma interactions

Sanjeev Herr, Sena Oten, Joshua D Bernstock, John D Rolston and Shawn L Hervey-Jumper
Neuro-oncology advances, v 8(Suppl 3), pp iii4-iii12
01 May 2026
PMID: 42221980
url
https://doi.org/10.1093/noajnl/vdaf109View
Published, Version of Record (VoR) Open

Abstract

Supplement
Increasing evidence has identified a complex relationship between neurons and malignant glial cells, leading to the rapid expansion of the field of cancer neuroscience. Of particular interest is the demonstrated ability of gliomas to integrate into functional neuronal networks of the brain. The extent of these interactions and the ability of these connections to influence and remodel circuits remains incompletely understood. Emerging technologies have allowed the mapping and monitoring of the structural and functional networks of the brain and, more recently, the interrogation of malignant glioma circuits. This review provides insight into how these tools and techniques may be leveraged to understand neuron-glioma interactions, establishing a crossroads between functional neurosurgery and neuro-oncology.

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Collaboration types
Domestic collaboration
Web of Science research areas
Clinical Neurology
Oncology
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