Files and links (1)
Published, Version of Record (VoR)Open Access (License Unspecified), Open
Journal article
Life Course Socioeconomic Status and Longitudinal Accumulation of Allostatic Load in Adulthood: Multi-Ethnic Study of Atherosclerosis
American journal of public health (1971), v 104(4), pp E48-E55
01 Apr 2014
PMID: 24524526
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objectives. We examined the association of childhood and adult socioeconomic status with longitudinal change in allostatic load (AL), a measure of biological dysfunction.
Methods. The study sample included 6135 participants from the Multi-Ethnic Study of Atherosclerosis, aged 45 to 84 years, recruited in 2000 from 6 US counties; 3 follow-up examinations took place through September 2011. We calculated standardized scores for several metabolic and cardiovascular components relative to accepted clinical cut points for "higher risk" and then summed them to create an overall index of AL. We used mixed effects growth curve models to assess the relationship between socioeconomic status and AL as a linear function of time passed since the baseline examination; we included random effects for the intercept and slope.
Results. Among those with lower baseline AL (< median), high adult education was associated with a significantly slower increase in AL over time, whereas there was no significant association among those with higher baseline AL.
Conclusions. The relationship between socioeconomic status and patterns of change in health parameters may vary over time and with the accumulation of biological risk.
Metrics
Details
- Title
- Life Course Socioeconomic Status and Longitudinal Accumulation of Allostatic Load in Adulthood: Multi-Ethnic Study of Atherosclerosis
- Creators
- Sharon Stein Merkin - University of WashingtonArun Karlamangla - College Station Medical CenterAna V. Diez Roux - Univ Michigan, Dept Epidemiol, Ann Arbor, MI 48109 USASandi Shrager - University of WashingtonTeresa E. Seeman - College Station Medical Center
- Publication Details
- American journal of public health (1971), v 104(4), pp E48-E55
- Publisher
- Amer Public Health Assoc Inc
- Number of pages
- 8
- Grant note
- UL1-RR-024156; UL1-RR-025005 / National Center for Research Resources; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) N01HC095159 / DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Eye Institute (NEI) N01-HC-95159; N01-HC-95160; N01-HC-95161; N01-HC-95162; N01-HC-95163; N01-HC-95164; N01-HC-95165; N01-HC-95166 / National Heart, Lung, and Blood Institute; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) UL1RR024156 / NATIONAL CENTER FOR RESEARCH RESOURCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Research Resources (NCRR) R01HL101161 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) R01 HI101161 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Drexel University
- Web of Science ID
- WOS:000341789200014
- Scopus ID
- 2-s2.0-84896539129
- Other Identifier
- 991020100056604721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health