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Journal article
Liver Cancer–Specific Serine Protease Inhibitor Kazal Is a Potentially Novel Biomarker for the Early Detection of Hepatocellular Carcinoma
Clinical and translational gastroenterology, v 11(12), pp e00271-e00271
23 Nov 2020
PMID: 33512798
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Liver cancer–secreted serine protease inhibitor Kazal (LC-SPIK) is a protein that is specifically elevated in cases of hepatocellular carcinoma (HCC). We assessed the performance of LC-SPIK in detecting HCC, including its early stages, in patients with cirrhosis, hepatitis B virus (HBV), and hepatitis C virus (HCV).
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Details
- Title
- Liver Cancer–Specific Serine Protease Inhibitor Kazal Is a Potentially Novel Biomarker for the Early Detection of Hepatocellular Carcinoma
- Creators
- Felix Lu - ImCare BiotechPir Ahmad Shah - Beth Israel Deaconess Medical CenterAbhishek Rao - ImCare BiotechCynthia Gifford-Hollingsworth - Drexel UniversityAnne Chen - ImCare BiotechGary Trey - Beth Israel Deaconess Medical CenterMina Soryal - ImCare BiotechArslan Talat - Beth Israel Deaconess Medical CenterAysha Aslam - Beth Israel Deaconess Medical CenterBilal Nasir - Beth Israel Deaconess Medical CenterSaad Choudhry - Beth Israel Deaconess Medical CenterRizwan Ishtiaq - Beth Israel Deaconess Medical CenterHanna Sanoff - University of North Carolina at Chapel HillLanla F. Conteh - James Cancer HospitalAnne Noonan - James Cancer HospitalKe-Qin Hu - University of California, IrvineCarl Schmidt - West Virginia UniversityMin Fu - SpringhouseJesse Civan - Thomas Jefferson UniversityGary Xiao - Drexel UniversityDaryl T.-Y. Lau - Beth Israel Deaconess Medical CenterXuanyong Lu - ImCare Biotech (United States)
- Publication Details
- Clinical and translational gastroenterology, v 11(12), pp e00271-e00271
- Publisher
- Wolters Kluwer
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Microbiology and Immunology
- Web of Science ID
- WOS:000607323000014
- Scopus ID
- 2-s2.0-85100539195
- Other Identifier
- 991019167458504721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Web of Science research areas
- Gastroenterology & Hepatology