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Liver disease following occupational exposure to 1,1,1‐trichloroethane: A case report
Journal article   Peer reviewed

Liver disease following occupational exposure to 1,1,1‐trichloroethane: A case report

Chaim Cohen and Arthur L Frank
American journal of industrial medicine, v 26(2), pp 237-241
Aug 1994
PMID: 7977399

Abstract

occupational liver disease organic solvents occupational history methyl chloroform 1,1,1‐trichloroethane hepatotoxicity
A patient with a progressive liver disease whose job involved substantial exposure to 1,1,1‐trichloroethane (TCE) was seen. A comprehensive work‐up ruled out nonoccupational etiologies for his liver condition. Neither the patient's history nor his liver histology suggested alcoholic cirrhosis. Removal of the patient from exposure to TCE led to significant improvement of his impaired liver function over a 3‐month period. We conclude that this was a case of occupational liver disease induced by chronic exposure to TCE. This report joins other reports concerning hepatotoxicity of TCE which is considered the least toxic among the halogenated hydrocarbon solvents.

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Web of Science research areas
Public, Environmental & Occupational Health
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