Journal article
Lobar pilocytic astrocytomas of the cerebral hemispheres: I. Diagnosis and nosology
Clinical neuropathology, v 13(6), pp 295-305
Nov 1994
PMID: 7851044
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This study provides neuropathological and neuroradiological observations on 11 cases of lobar pilocytic astrocytomas of the cerebral hemispheres, reappraising potential diagnostic caveats. These tumors may show variable degrees of contrast enhancement on computed tomography, as well as gadolinium uptake on magnetic resonance imaging, making them indistinguishable from malignant gliomas. Histopathologically, although typically pilocytic, they may exhibit areas of increased cellular density with protoplasmic and multinucleated glial elements (pilo-protoplasmic astrocytoma). The presence and particularly the abundance of distinct gliodegenerative structures, i.e. eosinophilic granular bodies (EGBs) and to a lesser degree Rosenthal fibers, in conjunction with collateral clinical, histologic and imaging parameters may facilitate oncotypic diagnosis. Mixed pilocytic and fibrillary astrocytomas are recognized, while malignant change may also rarely occur in longstanding lobar pilocytic astrocytomas.
Metrics
11 Record Views
Details
- Title
- Lobar pilocytic astrocytomas of the cerebral hemispheres: I. Diagnosis and nosology
- Creators
- C D Katsetos - Department of Pathology, Hahnemann University, Philadelphia, Pennsylvania 19102-1192L Krishna
- Publication Details
- Clinical neuropathology, v 13(6), pp 295-305
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:A1994PR39400001
- Scopus ID
- 2-s2.0-0028080095
- Other Identifier
- 991019346723204721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Pathology