Journal article
Long-Term Quality of Life in Prostate Cancer Patients Treated With Cesium-131
International journal of radiation oncology, biology, physics, v 98(5), pp 1053-1058
01 Aug 2017
PMID: 28721888
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
To evaluate long-term patient-reported quality of life (QOL) scores in men with prostate cancer treated at our institution with 131Cs prostate brachytherapy.
Patients treated more than 4 years ago with 131Cs (n=290) were asked to fill out an Expanded Prostate Cancer Index Composite (EPIC) QOL questionnaire and American Urological Association Symptom Score (AUASS) survey, before treatment and at each follow-up appointment. We compared patients' EPIC and AUA scores at baseline with scores at a last follow-up of at least 4 years after treatment using the Wilcoxon signed-rank test.
At a median last follow-up of 5.5 years after treatment with 131Cs prostate brachytherapy there were no clinically significant changes in the EPIC or AUA scores from baseline. There was statistical worsening in the EPIC urinary incontinence subscore. Subset analyses revealed improved QOL outcomes in patients who received external beam radiation therapy or α-blocker therapy, whereas androgen deprivation therapy was not associated with differences in QOL change.
Our results demonstrate minimal long-term changes in urinary or bowel patient-reported QOL with 131Cs prostate brachytherapy. These findings suggest that patients treated with this isotope are able to recover and then maintain their baseline QOL in the long term.
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Details
- Title
- Long-Term Quality of Life in Prostate Cancer Patients Treated With Cesium-131
- Creators
- Scott M. Glaser - UPMC Hillman Cancer CenterKatherine S. Chen - University of PittsburghRonald M. Benoit - University of Pittsburgh Medical CenterRyan P. Smith - UPMC Hillman Cancer CenterSushil Beriwal - UPMC Hillman Cancer Center
- Publication Details
- International journal of radiation oncology, biology, physics, v 98(5), pp 1053-1058
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:000405461700016
- Scopus ID
- 2-s2.0-85022074713
- Other Identifier
- 991021897393904721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging